Lactate clearance cut off for early mortality prediction in adult sepsis and septic shock patients

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Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.

OBJECTIVE Serial lactate concentrations can be used to examine disease severity in the intensive care unit. This study examines the clinical utility of the lactate clearance before intensive care unit admission (during the most proximal period of disease presentation) as an indicator of outcome in severe sepsis and septic shock. We hypothesize that a high lactate clearance in 6 hrs is associate...

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Is lactate clearance impaired in septic shock?

In a recent article in Critical Care, Tapia and colleagues evaluated the relationship between exogenous lactate clearance and liver perfusion in a short-term model of endotoxemic shock [1]. The authors concluded that the very low portal-hepatic vein lactate gradient was indicative of the inability of the liver to metabolize the increased lactate load. Although we believe that the authors addres...

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Early actate levelsfor prediction of mortality in patients with sepsis or septic shock: a meta-analysis

Purpose: Early verification of septic patients at a higher risk of death is still a challenge. There exist several controversies that lactate measurement in septic patients predicted mortality. The present study aimed to explore the diagnostic accuracy of elevated early lactate levels in predicting mortality in septic or septic shock patients. Methods: Three databases including PubMed, Embase a...

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Lactate clearance for death prediction in severe sepsis or septic shock patients during the first 24 hours in Intensive Care Unit: an observational study

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Diastolic dysfunction and mortality in severe sepsis and septic shock.

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ژورنال

عنوان ژورنال: IOP Conference Series: Earth and Environmental Science

سال: 2018

ISSN: 1755-1307,1755-1315

DOI: 10.1088/1755-1315/125/1/012023